These collectibles can be traded to permanently enhance his constitution.

The Vatican City introduces the first iteration of this quest and houses 15 Medicine Bottles dotted throughout the area.

Here’s where to find each one.

A Vatican City Medicine Bottle lying on a table in Indiana Jones And the Great Circle.

Shell mention ashortage of medicinesandrequest you to bring her any Medicine Bottles you find.

The first book of each series costs five bottles, with each subsequent upgrade increasing by five more.

Most of them arefound in areas patrolled by Blackshirts, so be cautious.

Indy holding a Vatican City Ancient Relic in Indiana Jones And The Great Circle.

If yousnag one in their presence, they’llraise the alarm.

Alwaysensure the coast is clearbefore making your move.

Location

Image

Description

Belvedere Courtyard

Inside thesoutheastern tent.

Indy in front of the pharmacist Valeria in Indiana Jones and the Great Circle.

However, aguard stationed in the nearby security boothwon’t make stealing it easy.

Take care of him first before collecting the Medicine Bottle.

Inside a fascist tentwith oil barrels inthe restricted area of Belvedere Courtyard.

Indiny stealing a Medicine Bottle in the Vatican City in Indiana Jones and the Great Circle.

Borgia Courtyards

On a tableoutside the Sistine Chapel.

Youll find this one resting on a wooden crate.

Apostolic Palace

Headeast from the Borgia Courtyards to reach the Apostolic Palaceentrance.

The Vatican Map showing the first Medicine Bottle location in Indiana Jones and the Great Circle.

The Medicine Bottle isunderneath the staircasejust inside.

Inside the dead-end alley, you’ll find the Medicine Bottle on a table.

Vatican Post Office

Head into thealleyway behind the Vatican Post Office.

Map showing Indy’s location near the second Medicine Bottle in Indiana Jones and The Great Circle.

You’ll spot theMedicine Bottle resting on a small wooden tablenear a fascist propaganda poster on the wall.

Blackshirt Barracks

Outside the barracks,climb the scaffoldingtoreach an overhang.

Inside, you’ll find the Medicine Bottle.

The map showing Indy’s location in front of the third Medicine Bottle in Indiana Jones and The Great Circle.

Inside one of the barracks thatunlocks with the Blackshirt Key.

Youll find the Medicine Bottleresting on a bench inside.

To get this Medicine Bottle, you’llneed to startthe Mad Priestquestand progress until youacquire the Sewer Key.

The Vatican Map showing the fourth Medicine Bottle location in Indiana Jones and the Great Circle.

Laundry Area

On a bench in the laundry area.

Work your way around the balcony, and you’llfind the Medicine Bottle beside a zipline.

The guns in Indiana Jones And The Great Circle can be confusing.

The Vatican Map showing the fifth Medicine Bottle location in Indiana Jones and the Great Circle.

you’re free to use them as melee weapons and only reload certain ones.

The Vatican Map showing the sixth Medicine Bottle location in Indiana Jones and the Great Circle.

The Vatican Map showing the seventh Medicine Bottle location in Indiana Jones and the Great Circle.

The Vatican Map showing the eighth Medicine Bottle location in Indiana Jones and the Great Circle.

The Vatican Map showing the ninth Medicine Bottle location in Indiana Jones and the Great Circle.

The Vatican Map showing the tenth Medicine Bottle location in Indiana Jones and the Great Circle.

The Vatican Map showing the 11th Medicine Bottle location in Indiana Jones and the Great Circle.

The Vatican Map showing the 12th Medicine Bottle location in Indiana Jones and the Great Circle.

The Vatican Map showing the 13th Medicine Bottle location in Indiana Jones and the Great Circle.

The Vatican Map showing the 14th Medicine Bottle location in Indiana Jones and the Great Circle.

The Vatican Map showing the 15th Medicine Bottle location in Indiana Jones and the Great Circle.

Indy pointing a gun at the Sphinx in Indiana Jones and the Great Circle.

Triple-A Games

Indiana Jones and the Great Circle